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Theses/Dissertations from 2012

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THE EFFECT OF ACUTE EXERCISE ON THE PRODUCTION OF REACTIVE OXYGEN SPECIES AND INFLAMMATORY MARKERS IN HEALTHY PRE-PUBERTAL AND ADULT MALES, Maple Liu

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MODEL-BASED COST-CONSEQUENCE ANALYSIS OF POSTOPERATIVE TROPONIN T SCREENING IN PATIENTS UNDERGOING NONCARDIAC SURGERY, Giovanna AL Lurati Buse

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Procoagulant effects of lung cancer chemotherapy on HUVEC, A549 cells, and monocytes., Zakhar Lysov

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The Regulation of Brain Serotonergic and Dopaminergic Neurons: The Modulatory Effects of Selective Serotonin Reuptake Inhibitors, Atypical Neuroleptics and Environmental Enrichment, Lindsey E.S. MacGillivray

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FUNCTION OF YJEE AND RIBOSOME ASSEMBLY FACTORS, Chand S. Mangat

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A Mobile Tablet App for Clinical Evaluation and Medical Education: Development and Usability Evaluation, Deepa A. Mathew

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Bayesian Approaches for Synthesising Evidence in Health Technology Assessment, Catherine Elizabeth McCarron

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CHARACTERIZATION AND APPLICATION OF SELF-PHOSPHORYLATING DEOXYRIBOZYMES, Simon A. McManus

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Impact of Commensal Intestinal Microbiota on Nervous System Development and Function, Karen-Anne McVey Neufeld PhD

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Succeeding in Level 1 of a BScN Program: A Grounded Theory Inquiry, Carrie J. Mines

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GLUCOSE SUPPLEMENTATION AND MEASURES OF OXIDATIVE STRESS IN PATIENTS WITH GLYCOGEN PHOSPHORYLASE DEFICIENCY (MCARDLE’S DISEASE)., Nicholas Joseph Mocellin

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DECODING TOXICITY: CHARACTERIZATION OF THE IBSC/SIBC TYPE I TOXIN-ANTITOXIN SYSTEM OF ESCHERICHIA COLI, Wendy (Wing Ki) Mok

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Investigation of the interaction of multimerin 1 with components of prothrombinase, in vitro, Zainab A. Motala

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CHARACTERIZING THE FUNCTION OF HUNTINGTIN IN THE CELL STRESS RESPONSE AS A TARGET FOR DRUG DISCOVERY IN HUNTINGTON’S DISEASE, Lise N. Munsie

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A CLUSTER RANDOMIZATION TRIAL TO TEST THE EFFECTIVENESS OF A CLINICAL PATHWAY IN MANAGING ATRIAL FIBRILLATION IN THE EMERGENCY DEPARTMENT, Girish Madhavan Nair

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Delineating the Role of TCF3 in Mouse Embryonic Stem Cell Self-Renewal and Differentiation, Deborah Ng

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THE DEVELOPMENT OF A MODEL SYSTEM FOR THE CHARACTERIZATION OF CANCER STEM CELL PROPERTIES IN BRAIN METASTASES FROM THE LUNG, Sara M. Nolte

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The Role of TIM-4 in the Intestinal Inflammation, Natasha Nurtanio

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Design and Evaluation of Two Way Interactive Video eConsult System (TWIVES): A Web-Based Care and Continuity Solution Enabling Secure and Private Patient-Provider Connections, Kenneth C. Nwosu

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Discovery and Characterization of Ibomycin: An Anticryptocccal Metabolite Produced by WAC 2288, Jonathan S. O'Brien

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Person Centred Palliative Care: A First Nations Perspective, Valerie A. O'Brien

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Cis-Regulatory Evolution in Salmonella enterica, Suzanne Osborne

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Electronic Strategies to Enhance Venous Thromboprophylaxis in Hospitalized Medical Patients: A Randomized Controlled Trial, Menaka Pai

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SYSTEMATIC REVIEW OF EQ-5D VAULATION STUDIES, Kuhan Perampaladas

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INVESTIGATION OF THE CYTOPROTECTIVE EFFECTS OF SONIC HEDGEHOG IN CELLULAR AND ANIMAL MODELS OF AMYOTROPHIC LATERAL SCLEROSIS, Randy Peterson

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Evaluation of an early biomarker panel for the identification of emergency department patients at high risk for a short term cardiac outcome, Kim Phan

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The Requirement of Matrix Metalloproteinase 2 and 9 in Transforming Growth Factor Beta Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells, Giuseppe Pino

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Mechanisms Underlying Rhythmic Activities of the Gastrointestinal Tract, Marc J. Pistilli

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TESTING FOR TREATMENT HETEROGENEITY BETWEEN THE INDIVIDUAL OUTCOMES WITHIN A COMPOSITE OUTCOME, Janice M. Pogue

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ETV5 as a Regulator of Matrix Metalloproteinase 2 in Human Chondrosarcoma, Patricia F. Power

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Mechanisms Underlying the Immunopathology in Heterologous Pulmonary Infection, ELENA PRETUS

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PERCEPTIONS OF ONTARIO’S FIRST UPCOMING DRUG INFORMATION SYSTEM (DIS): NARRATING THE STORY OF CONSUMERS, PRESCRIBERS AND DISPENSERS, Hafsa Qureshi

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BLOOD PRESSURE CHANGES BY AGE FROM CHILDHOOD TO ADOLESCENCE IN SOUTH ASIAN CHILDREN, Manu Raj

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EXAMINING DETERMINANTS OF INSULIN RESISTANCE IN ADULTS BORN AT NORMAL AND EXTREMELY LOW BIRTH WEIGHT, Laura Ramsingh

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Accounting for centre in the Early External Cephalic Version trials: An empirical comparison of statistical methods to account for centre in multicentre randomised controlled trials with binary outcomes, Angela H. Reitsma

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Fusing the C-terminal tridecapeptide of hirudin to α1-proteinase inhibitor M358R accelerates its rate of thrombin inhibition, Leigh Ann C. Roddick

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Direct Conversion of Fibroblasts to Hematopoietic Progenitors, Linda Rodriguez

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A Mouse Model of Deep Vein Thrombosis Stability: The Effect of Direct Thrombin Inhibition, Lisa J. Saldanha

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THE ROLE OF AMP-ACTIVATED PROTEIN KINASE (AMPK) IN MEDIATING RADIATION RESPONSES IN CANCER CELLS, Toran Sanli

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The Regulation of Vascular Wall Cells by a TLR Ligand and Gp130 Cytokines, David L.K. Schnittker

CHARACTERIZATION OF CHILDREN AT-RISK FOR DEVELOPING ANXIETY DISORDERS: FINDINGS FROM CLINICAL ASSESSMENTS, BEHAVIOURAL DATA AND FUNCTIONAL MAGNETIC RESONANCE IMAGING, Rhandi Senaratne

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CHARACTERIZING CBID AND BAX BINDING TO SUPPORTED LIPID BILAYERS WITH SINGLE MOLECULE RESOLUTION, Sanjeevan Shivakumar

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Properties of Two Enzymes Involved in the Phosphoinositide Cycle – Diacylglycerol Kinase and Phosphatidylinositol 4-Phosphate 5-Kinase, Yulia V. Shulga

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Transition to Parenthood for First-Time Fathers Whose Partners have Postpartum Depression, Janet T. Siverns

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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF THE CHLAMYDIA PNEUMONIAE TYPE III SECRETION SYSTEM, Christopher B. Stone

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MOLECULAR RESPONSES OF LUNG CANCER TO IONIZING RADIATION: INVESTIGATION OF THE BIGUANIDE METFORMIN IN COMBINATION WITH IONIZING RADIATION, Yaryna Storozhuk

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ROLE OF THE PSEUDOMONAS AERUGINOSA INNER MEMBRANE PROTEIN PILC IN TYPE IV PILUS FUNCTION, Herlinder K. Takhar

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Magnetic Resonance and Radiography in Rheumatoid Arthritis: Intermodality Comparisons of Erosion Detection, Ruben V. Tavares

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CHARACTERIZATION OF MARCO-MEDIATED ENDOCYTOSIS, Zhongyuan Tu

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System xc- Mediated Glutamate Transport Inhibition in Cancer-Induced Bone Pain, Robert G. Ungard

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THE UNMET SUPPORTIVE CARE NEEDS OF PATIENTS WITH NEWLY DIAGNOSED ADVANCED COLON CANCER, Suganya Vadivelu Mrs.

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MATERNAL PRE-PREGNANCY BODY MASS INDEX, MACROSOMIA, AND MENTAL HEALTH IN CHILDREN AND ADOLESCENTS, Ryan J. Van Lieshout MD, PhD, FRCP(C)

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The Type 1 Fimbrial Adhesin Mediates the Interaction of Adherent-Invasive Escherichia coli with the Host, Lauren E. Wallar

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THE ROLE OF SREBP-1 IN MEDIATING ANGIOTENSIN II- INDUCED KIDNEY FIBROSIS, Nuo Wang

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Discovery of conserved motifs in MARCO through evolutionary analyses and molecular biology, Fiona J. Whelan

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Elafin in Intestinal Barrier Fortification: A Potential Adjuvant Therapy for Gluten Intolerance, Michelle C. Wiepjes

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A two step mechanism for activation of actinorhodin export and resistance in Streptomyces coelicolor, Ye Xu

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Alanine Transaminase and Waist to Hip Ratio as Predictors of Dysglycemia and Regression to Normoglycemia in Adult Patients with Prediabetes, Natalia Yakubovich

Theses/Dissertations from 2011

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PRIMARY CARE DIABETES: ISSUES FACING FAMILY DOCTORS, Gina Agarwal

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Family Physician Continuity of Care in End-of-Life Homecare Cancer Patients and its Association with Acute Care Services Use, Ummukulthum A. Almaawiy

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Psychometric Methods to Develop and to Analyze Clinical Measures: A Comparison and Contrast of Rasch Analysis and Classical Test Theory Analysis of the PedsQL 4.0 Generic Core Scales (Parent-report) in a Childhood Cancer Sample, Leila Amin

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Functional Structures: The Role of XRCC4 and XLF in Mammalian DNA Double-Strand Break Repair, Sara N. Andres

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Immune-Effector Pathways Leading To Peanut-Induced Anaphylaxis, Katherine Arias

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EXAMINING PALLIATIVE CARE NETWORKS IN ENHANCING COMMUNITY PALLIATIVE CARE, Daryl Bainbridge

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Reporting of Influenza-Related Events, Angela M. Barbara

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Adiponectin Receptor 1 and Liver Kinase B1 are Downregulated in Renal Cell Carcinoma, Laura Beatty

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PAOPA, a potent dopamine D2 receptor allosteric modulator, prevents and reverses behavioural and biochemical abnormalities in an amphetamine-sensitized preclinical animal model of schizophrenia., Michael G.R. Beyaert

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INVESTIGATION OF ANTIBIOTIC RESISTANCE IN ISOLATED LECHUGUILLA CAVE STRAINS, Kirandeep Bhullar

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Assessment of Bone Geometry in Postmenopausal Women with Osteoporosis of the Spine Before and After a 6 Month Aquatic Exercise Program, Alison M. Bonnyman

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THE RELIABILITY AND VALIDITY OF THE PSFS IN PEOPLE WITH PD, Gabriela Burgos-Martinez

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Impact of intestinal microbial composition on the regulation of immunoglobulin E, Julia Cahenzli

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LENGTHENED G1 PHASE INDICATES DIFFERENTIATION STATUS IN HUMAN EMBRYONIC STEM CELLS., Ashley Calder

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STRUCTURAL INSIGHTS INTO THE ROLES OF SEQA ON ORIGIN SEQUESTRATION AND CHROMOSOME ORGANIZATION, Yu Seon Chung

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Alterations in the Intestinal Microbiota Can be Detected by and Influence Specific Brain Regions, Josh Collins

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The routine use of the Canadian Occupational Performance Measure by Occupational Therapists: Effect on practice, outcomes and therapists' perceptions of use, Heather Colquhoun

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A Narrative Study of the Older Patient and Family Caregiver Experience of Alternate Level of Care, Greg Cressman

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EFFECT OF SMOKING AND CESSATION IN HIV-INFECTED PEOPLE, Qu Cui

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Oral Pharmacotherapy for Relapsing-Remitting Multiple Sclerosis: Systematic Review and Indirect Treatment Comparison, Brett M. Doble

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VALIDITY OF PRE-DISCHARGE FUNCTIONAL MEASURES FOR PREDICTING HARM IN OLDER ADULTS, Alison Douglas

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Empowering Ontario Public Health Nurses to Address the Causes of Poverty: A Qualitative Descriptive Study, Jeri A. Dunne

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CONTENT ISSUES IN CHILD HEALTH STATUS AND QUALITY OF LIFE INSTRUMENTS: ADDRESSING THE CHALLENGES WITH NEW METHODS, Nora Fayed

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The Engineering of Riboswitch-Based Sensors of Small Molecules in Bacteria and Their Application in the Study of Vitamin B12 Biology, Casey C. Fowler

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NON-TRAUMATIC FRACTURES IN INDIVIDUALS WITH DIABETES, Lisa-Ann Fraser

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THEORETICAL STUDY OF STATE-DEPENDENT ACTION OF TOXINS AND DRUGS IN A VOLTAGE GATED SODIUM CHANNEL, Daniel Garden

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PRENATAL CARE IN TWO NUNAVUT COMMUNITIES: THE BARRIERS, FACILITATORS AND MOTIVATORS TO UTILIZING CARE, Johanna Geraci

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A HIGH-THROUGHPUT SCREEN TO IDENTIFY SMALL MOLECULES THAT SELECTIVELY TARGET TUMOR-INITIATING CELLS IN A MOUSE MODEL OF HER2-INDUCED BREAST CANCER, Andrew O. Giacomelli

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Modulation of Airway Smooth Muscle Proliferation, Migration, Contractility and Cytokine Synthesis by Human Adipocytes, Amanda LA Giesler

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SELECTION OF CELL-INTERNALIZING CIRCULAR DNA APTAMERS, Jimmy Gu

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REVISED STRATEGY OF SYNCOPE DIAGNOSIS IN THE EMERGENCY ROOM AT THE GENERAL HOSPITAL (RESASTER): A CLUSTER RANDOMIZED TRIAL, Juan C. Guzman

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The Development of Protocols to Engineer and Screen Streptomyces in High Throughput to Test for the Activation of Cryptic Clusters by the Heterologous Expression of Pleiotropic Regulators, Tomas A. Gverzdys

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NEIGHBOURHOOD AND SOCIAL INFLUENCES ON PARTICIPATION IN EVERYDAY ACTIVITIES AMONG OLDER ADULTS WITH CHRONIC HEALTH CONDITIONS, Carri Hand

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ASPECTS OF AIRWAY STRETCH-ACTIVATED CONTRACTIONS ASSESSED IN PERFUSED INTACT BOVINE BRONCHIAL SEGMENTS, Jeremy M. Hernandez

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The Function of RKIP in the Tumourigenesis of Clear Cell Renal Cell Carcinoma, Brianne Hill

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HOW COMMUNITY-BASED SERVICES WORK TOGETHER TO ADDRESS THE PRIMARY HEALTH CARE NEEDS OF RECENT IMMIGRANT CHILDREN, Sandra M. Isaacs

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A Study About Personalized Academic Detailing - Pilot Project on Smoking Cessation, Margaret Jin

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The Changing Nature of Health Professionals' Work: The Impact of Infectious Disease, Alyshah Kaba

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External Validation of the Orebro Musculoskeletal Pain Screening Questionnaire within an Injured Worker Population: A Retrospective Cohort Study, Rhonda Kirkwood

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Inhibition of Notch signaling targets breast tumor initiating cells, Maria Kondratyev

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DIABETIC MYOPATHY: CHANGES TO CONTRACTILE FUNCTION, MORPHOLOGY AND REGENERATIVE CAPACITY OF SKELETAL MUSCLE IN A MURINE MODEL OF TYPE 1 DIABETES MELLITUS, Matthew P. Krause

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Understanding Sex/Gender in Cardiovascular Disease, Catherine Kreatsoulas