Theses/Dissertations from 2013
INDUCTION OF NEUROTROPHIC AND DIFFERENTIATION GENES IN NEURAL STEM CELLS BY VALPROIC ACID, Walaa Saeed Almutawaa
The Role of Periostin in Promoting the Progression of Clear Cell Renal Cell Carcinoma, Nazihah Bakhtyar
Lung Immunopathology Following Influenza And Pneumococcus Infection: Mechanisms Of Disease And Therapeutic Approaches, Daniela Damjanovic
MECHANISMS OF TGFβ ACTIVATION IN LUNG FIBROSIS, Aaron Froese
EXPOSURE TO CIGARETTE SMOKE AND ITS IMPACT ON THE OVARIAN FOLLICLE POPULATION: MECHANISMS OF FOLLICLE LOSS, Anne M. Gannon
INVESTIGATION OF CD36 SCAVENGER TYPE B RECEPTOR EXPRESSING MACROPHAGES IN INTESTINAL INFLAMMATION, Elizabeth Alexandera Garside
NONINVASIVE IMAGING OF LUNG PATHOLOGY AND PHYSIOLOGY IN MURINE MODELS OF ASTHMA AND COPD, Brian N. Jobse
MODELING AND MECHANISTIC INSIGHTS INTO THE DEVELOPMENT OF ALLERGIC AIRWAY RESPONSES TO HOUSE DUST MITE, Alba Llop Guevara
ADAPTIVE EVENTS IN THE TUMOR LIMIT THE SUCCESS OF CANCER IMMUNOTHERAPY, AJ Robert McGray
DOES FOLIC ACID SUPPLEMENTATION PREVENT NICOTINE-INDUCED BETA CELL DYSFUNCTION, Catherine J. Nicholson
The role of Xin in skeletal muscle regeneration, Aliyah A. Nissar
The Assessment of Structural and Material Bone Qualities in Adults with Type 2 Diabetes, Janet M. Pritchard
Influence of maternal atopy and innate and adaptive immune stimuli on cord blood hematopoietic progenitor cells, Pia-Lauren Reece
β-catenin overexpression within the metanephric mesenchyme causes renal dysplasia via upregulation of the Gdnf signalling axis, Sanjay Sarin
EFFECTS OF VALPROIC ACID ON EXPRESSION OF THE MELATONIN RECEPTORS MT1 AND MT2, AND THE NEUROTROPHIC FACTORS BDNF AND GDNF IN VIVO, Arani Sathiyapalan
LUNG-HOMING OF ENDOTHELIAL PROGENITOR CELLS AND ANGIOGENESIS IN ASTHMA: ROLE OF EOSINOPHILS, Nirooya Sivapalan
THE EFFECTS OF PPAR AGONISTS ON EOSINOPHIL FUNCTION, Steven G. Smith
IMPROVING ONCOLYTIC VESICULAR STOMATITIS VIRUS THROUGH MODULATION OF THE ANTI-TUMOUR IMMUNE RESPONSE, Kyle B. Stephenson
HOPX EXPRESSION IN IMMUNE REGULATORY B CELL REGULATE INTESTINAL INFLAMMATION, Nalayini Thayaparana Nala
Theses/Dissertations from 2012
VIRAL-ALLERGEN INTERACTIONS: INSIGHTS INTO THE ORIGINS OF ALLERGIC ASTHMA., Amal Al-Garawi
THE ROLE OF NEUTROPHILS IN SEVERE ASTHMA, Afia Aziz-ur-Rehman
CONTRIBUTION OF THE UNFOLDED PROTEIN RESPONSE (UPR) TO ADIPOGENESIS AND WHOLE BODY ENERGY HOMEOSTASIS, Sana Basseri
Gastrointestinal-Sparing Effects of Novel NSAIDs in Rats with Compromised Mucosal Defence, Rory W. Blackler
THE ROLE OF INTERFERON REGULATORY FACTOR 3 IN THE INNATE ANTIVIRAL RESPONSE, Tracy Chew
CHARACTERIZATION OF CHLAMYDIA PNEUMONIAE CDSD AND ITS ROLE IN THE BASAL BODY OF THE TYPE III SECRETION APPARATUS, Robert C. Clayden
In Silico Modelling of Complex Biological Processes with Applications to Allergic Asthma and Cancer, Marc Colangelo
Parathyroid hormone-related protein in giant cell tumour of bone, Robert W. Cowan
The Effect of Goblet Cell Metaplasia On Airway Barrier Integrity, Christopher J. Dalle Ave
Effects of Extreme Temperature on Airway Smooth Muscle Cell Death, Lindsay E. DoHarris
Correlates of Mucosal Humoral Immunity in Peripheral Blood, Jason R. Fernandes
Eukaryotic and Prokaryotic Sources of Colonic Hydrogen Sulfide Synthesis, Kyle L. Flannigan
ASPECTS OF HUMAN RHINOVIRUS INFECTION IN HOSPITALIZED AND NON-HOSPITALIZED INDIVIDUALS, Andrea C. Granados
The effect of lifelong maternal obesity on pregnancy outcomes and placental development, Emily K. Hayes
INVOLVEMENT OF SRC TYROSINE KINASE AND CALCIUM-HANDLING IN AIRWAY SMOOTH MUSCLE EXCITATION-CONTRACTION COUPLING, Brent T. Humber
Fetal Origin of Chronic Immune Disease: Role of Prenatal Stress Challenge, Caitlin A. Jago
Targeting gp41 as a strategy to induce mucosal and humoral immunity against HIV-1, Sumiti Jain
The Effects of Bifidobacterium Longum NCC3001 on AH Neuron Excitability and Slow Wave Activity of the Mouse Intestine, Amir Khoshdel
The Impact of Macrophage Polarity and the Tumor Microenvironment on NK Cell Phenotype and Function, Tamara Krneta
THE ROLE OF GP130 CYTOKINES IL-6 AND OSM ON TUMOR DEVELOPMENT IN MOUSE MODELS FOR LUNG ADENOCARCINOMA, Sean Lauber
Characterization of CopN (Cpn0324) the Putative Type III Secretion System Plug Protein of Chlamydia pneumoniae, Tiffany L. Leighton
Procoagulant effects of lung cancer chemotherapy on HUVEC, A549 cells, and monocytes., Zakhar Lysov
The Regulation of Brain Serotonergic and Dopaminergic Neurons: The Modulatory Effects of Selective Serotonin Reuptake Inhibitors, Atypical Neuroleptics and Environmental Enrichment, Lindsey E.S. MacGillivray
Impact of Commensal Intestinal Microbiota on Nervous System Development and Function, Karen-Anne McVey Neufeld PhD
GLUCOSE SUPPLEMENTATION AND MEASURES OF OXIDATIVE STRESS IN PATIENTS WITH GLYCOGEN PHOSPHORYLASE DEFICIENCY (MCARDLE’S DISEASE)., Nicholas Joseph Mocellin
Investigation of the interaction of multimerin 1 with components of prothrombinase, in vitro, Zainab A. Motala
The Role of TIM-4 in the Intestinal Inflammation, Natasha Nurtanio
INVESTIGATION OF THE CYTOPROTECTIVE EFFECTS OF SONIC HEDGEHOG IN CELLULAR AND ANIMAL MODELS OF AMYOTROPHIC LATERAL SCLEROSIS, Randy Peterson
Mechanisms Underlying Rhythmic Activities of the Gastrointestinal Tract, Marc J. Pistilli
ETV5 as a Regulator of Matrix Metalloproteinase 2 in Human Chondrosarcoma, Patricia F. Power
Mechanisms Underlying the Immunopathology in Heterologous Pulmonary Infection, ELENA PRETUS
EXAMINING DETERMINANTS OF INSULIN RESISTANCE IN ADULTS BORN AT NORMAL AND EXTREMELY LOW BIRTH WEIGHT, Laura Ramsingh
Fusing the C-terminal tridecapeptide of hirudin to α1-proteinase inhibitor M358R accelerates its rate of thrombin inhibition, Leigh Ann C. Roddick
THE ROLE OF AMP-ACTIVATED PROTEIN KINASE (AMPK) IN MEDIATING RADIATION RESPONSES IN CANCER CELLS, Toran Sanli
The Regulation of Vascular Wall Cells by a TLR Ligand and Gp130 Cytokines, David L.K. Schnittker
STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF THE CHLAMYDIA PNEUMONIAE TYPE III SECRETION SYSTEM, Christopher B. Stone
MOLECULAR RESPONSES OF LUNG CANCER TO IONIZING RADIATION: INVESTIGATION OF THE BIGUANIDE METFORMIN IN COMBINATION WITH IONIZING RADIATION, Yaryna Storozhuk
Magnetic Resonance and Radiography in Rheumatoid Arthritis: Intermodality Comparisons of Erosion Detection, Ruben V. Tavares
CHARACTERIZATION OF MARCO-MEDIATED ENDOCYTOSIS, Zhongyuan Tu
System xc- Mediated Glutamate Transport Inhibition in Cancer-Induced Bone Pain, Robert G. Ungard
THE ROLE OF SREBP-1 IN MEDIATING ANGIOTENSIN II- INDUCED KIDNEY FIBROSIS, Nuo Wang
Elafin in Intestinal Barrier Fortification: A Potential Adjuvant Therapy for Gluten Intolerance, Michelle C. Wiepjes
Theses/Dissertations from 2011
Adiponectin Receptor 1 and Liver Kinase B1 are Downregulated in Renal Cell Carcinoma, Laura Beatty
PAOPA, a potent dopamine D2 receptor allosteric modulator, prevents and reverses behavioural and biochemical abnormalities in an amphetamine-sensitized preclinical animal model of schizophrenia., Michael G.R. Beyaert
Impact of intestinal microbial composition on the regulation of immunoglobulin E, Julia Cahenzli
Alterations in the Intestinal Microbiota Can be Detected by and Influence Specific Brain Regions, Josh Collins
Modulation of Airway Smooth Muscle Proliferation, Migration, Contractility and Cytokine Synthesis by Human Adipocytes, Amanda LA Giesler
ASPECTS OF AIRWAY STRETCH-ACTIVATED CONTRACTIONS ASSESSED IN PERFUSED INTACT BOVINE BRONCHIAL SEGMENTS, Jeremy M. Hernandez
The Function of RKIP in the Tumourigenesis of Clear Cell Renal Cell Carcinoma, Brianne Hill
DIABETIC MYOPATHY: CHANGES TO CONTRACTILE FUNCTION, MORPHOLOGY AND REGENERATIVE CAPACITY OF SKELETAL MUSCLE IN A MURINE MODEL OF TYPE 1 DIABETES MELLITUS, Matthew P. Krause
GENETIC DISRUPTION OF ACETYL COA CARBOXYLASE PHOSPHORYLATION BY AMP-ACTIVATED PROTEIN KINASE INCREASES LIVER LIPID ACCUMULATION AND INSULIN RESISTANCE, Katarina Marcinko
The Effect of Lactobacillus reuteri on Host Immune and Cell Alterations During an Enteric Parasitic Infection, Jessica M. McClemens
IRF9 AND NITRIC OXIDE: IMPORTANT ANTIVIRAL MEDIATORS IN THE ABSENCE OF KEY SIGNALLING MOLECULES, Devangi R. Mehta
THE INFLUENCE OF HOST STRESS ON THE GASTROINTESTINAL TRACT AND THE MICROBIOTA, Amber J. Park
CYTOKINE MODULATION OF PROGENITOR CELL MIGRATION, Navneet Punia
High-Intensity Interval Training Improves Insulin Sensitivity Independent of Adipose Tissue Inflammation, Sarah R. Sikkema
Cytokines as Biomarkers in Asthma, Elizabeth Simms
CHARACTERIZATION OF ΔM51-VSV EXPRESSING BECLIN1, Elspeth K. Smith Mrs.
Modulation of Hemostatic Pathways by Breast Cancer Chemotherapy Agents, Laura L. Swystun
Investigating the Pro-Atherogenic Potential of Chronic Hyperglycemia: Is Diabetic Atherosclerosis a Microvascular Complication?, Kaley J. Veerman
ANTICHOLINERGIC THERAPY IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE: NOVEL MECHANISMS OF ACTION, Aaron W. Young
Theses/Dissertations from 2004
The role of bone marrow inflammatory cell progenitors in allergen-induced asthma, Sandra Christine Dorman
Modulation of Intestinal Epithelial Physiology and Signal Transduction by Transforming Growth Factor-beta, Kathryn Howe
Dynamic and stable regulation of pyruvate dehydrogenase in human skeletal muscle, Paul-Jean LeBlanc
The uncoupling of the inflammatory and structural components of airway hyperresponsiveness, Richard Leigh
THE HIGH ENERGY COST OF WALKING IN CHILDREN AND ADOLESCENTS WITH SPASTIC CEREBRAL PALSY: PHYSIOLOGIC, ELECTROMYOGRAPHIC AND BIOMECHANICAL IMPLICATIONS, DESIREE B. MALTAIS
Novel cysteinyl leukotriene biology in human airways, Parameswaran K. Nair
Cell Cycle and HEB Mediated Regulation of Gene Expression during Myogenic Differentiation, Maura H. Parker
Role of ErbB3 During Mammary Tumorigenesis, Niki Sharan
IMMUNE REGULATORY MECHANISMS OF THE RESPIRATORY MUCOSA, FILIP KRZYSZTOF SWIRSKI
The role of β-integrin signaling in mammary gland tumourigenesis, Donald E. White
Investigation of Immunomodulatory Concepts in a Murine Model of Airway Mucosal Sensitization to Innocuous Antigen, Ryan E. Wiley
Theses/Dissertations from 2003
Molecular Abnormalities in Postmortem Brains of Subjects with Mood Disorders, Dariush Dowlatshahi