Theses/Dissertations from 2012
CONTRIBUTION OF THE UNFOLDED PROTEIN RESPONSE (UPR) TO ADIPOGENESIS AND WHOLE BODY ENERGY HOMEOSTASIS, Sana Basseri
THE ROLE OF INTERFERON REGULATORY FACTOR 3 IN THE INNATE ANTIVIRAL RESPONSE, Tracy Chew
In Silico Modelling of Complex Biological Processes with Applications to Allergic Asthma and Cancer, Marc Colangelo
Parathyroid hormone-related protein in giant cell tumour of bone, Robert W. Cowan
The Effect of Goblet Cell Metaplasia On Airway Barrier Integrity, Christopher J. Dalle Ave
Effects of Extreme Temperature on Airway Smooth Muscle Cell Death, Lindsay E. DoHarris
The effect of lifelong maternal obesity on pregnancy outcomes and placental development, Emily K. Hayes
INVOLVEMENT OF SRC TYROSINE KINASE AND CALCIUM-HANDLING IN AIRWAY SMOOTH MUSCLE EXCITATION-CONTRACTION COUPLING, Brent T. Humber
The Effects of Bifidobacterium Longum NCC3001 on AH Neuron Excitability and Slow Wave Activity of the Mouse Intestine, Amir Khoshdel
Procoagulant effects of lung cancer chemotherapy on HUVEC, A549 cells, and monocytes., Zakhar Lysov
The Regulation of Brain Serotonergic and Dopaminergic Neurons: The Modulatory Effects of Selective Serotonin Reuptake Inhibitors, Atypical Neuroleptics and Environmental Enrichment, Lindsey E.S. MacGillivray
Impact of Commensal Intestinal Microbiota on Nervous System Development and Function, Karen-Anne McVey Neufeld PhD
Investigation of the interaction of multimerin 1 with components of prothrombinase, in vitro, Zainab A. Motala
INVESTIGATION OF THE CYTOPROTECTIVE EFFECTS OF SONIC HEDGEHOG IN CELLULAR AND ANIMAL MODELS OF AMYOTROPHIC LATERAL SCLEROSIS, Randy Peterson
THE ROLE OF AMP-ACTIVATED PROTEIN KINASE (AMPK) IN MEDIATING RADIATION RESPONSES IN CANCER CELLS, Toran Sanli
STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF THE CHLAMYDIA PNEUMONIAE TYPE III SECRETION SYSTEM, Christopher B. Stone
System xc- Mediated Glutamate Transport Inhibition in Cancer-Induced Bone Pain, Robert G. Ungard
Theses/Dissertations from 2011
Adiponectin Receptor 1 and Liver Kinase B1 are Downregulated in Renal Cell Carcinoma, Laura Beatty
PAOPA, a potent dopamine D2 receptor allosteric modulator, prevents and reverses behavioural and biochemical abnormalities in an amphetamine-sensitized preclinical animal model of schizophrenia., Michael G.R. Beyaert
Impact of intestinal microbial composition on the regulation of immunoglobulin E, Julia Cahenzli
Alterations in the Intestinal Microbiota Can be Detected by and Influence Specific Brain Regions, Josh Collins
Modulation of Airway Smooth Muscle Proliferation, Migration, Contractility and Cytokine Synthesis by Human Adipocytes, Amanda LA Giesler
ASPECTS OF AIRWAY STRETCH-ACTIVATED CONTRACTIONS ASSESSED IN PERFUSED INTACT BOVINE BRONCHIAL SEGMENTS, Jeremy M. Hernandez
The Function of RKIP in the Tumourigenesis of Clear Cell Renal Cell Carcinoma, Brianne Hill
DIABETIC MYOPATHY: CHANGES TO CONTRACTILE FUNCTION, MORPHOLOGY AND REGENERATIVE CAPACITY OF SKELETAL MUSCLE IN A MURINE MODEL OF TYPE 1 DIABETES MELLITUS, Matthew P. Krause
GENETIC DISRUPTION OF ACETYL COA CARBOXYLASE PHOSPHORYLATION BY AMP-ACTIVATED PROTEIN KINASE INCREASES LIVER LIPID ACCUMULATION AND INSULIN RESISTANCE, Katarina Marcinko
The Effect of Lactobacillus reuteri on Host Immune and Cell Alterations During an Enteric Parasitic Infection, Jessica M. McClemens
IRF9 AND NITRIC OXIDE: IMPORTANT ANTIVIRAL MEDIATORS IN THE ABSENCE OF KEY SIGNALLING MOLECULES, Devangi R. Mehta
THE INFLUENCE OF HOST STRESS ON THE GASTROINTESTINAL TRACT AND THE MICROBIOTA, Amber J. Park
CYTOKINE MODULATION OF PROGENITOR CELL MIGRATION, Navneet Punia
High-Intensity Interval Training Improves Insulin Sensitivity Independent of Adipose Tissue Inflammation, Sarah R. Sikkema
Cytokines as Biomarkers in Asthma, Elizabeth Simms
CHARACTERIZATION OF ΔM51-VSV EXPRESSING BECLIN1, Elspeth K. Smith Mrs.
Modulation of Hemostatic Pathways by Breast Cancer Chemotherapy Agents, Laura L. Swystun
Investigating the Pro-Atherogenic Potential of Chronic Hyperglycemia: Is Diabetic Atherosclerosis a Microvascular Complication?, Kaley J. Veerman
ANTICHOLINERGIC THERAPY IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE: NOVEL MECHANISMS OF ACTION, Aaron W. Young
Theses/Dissertations from 2004
The role of bone marrow inflammatory cell progenitors in allergen-induced asthma, Sandra Christine Dorman
Modulation of Intestinal Epithelial Physiology and Signal Transduction by Transforming Growth Factor-beta, Kathryn Howe
Dynamic and stable regulation of pyruvate dehydrogenase in human skeletal muscle, Paul-Jean LeBlanc
The uncoupling of the inflammatory and structural components of airway hyperresponsiveness, Richard Leigh
THE HIGH ENERGY COST OF WALKING IN CHILDREN AND ADOLESCENTS WITH SPASTIC CEREBRAL PALSY: PHYSIOLOGIC, ELECTROMYOGRAPHIC AND BIOMECHANICAL IMPLICATIONS, DESIREE B. MALTAIS
Novel cysteinyl leukotriene biology in human airways, Parameswaran K. Nair
Cell Cycle and HEB Mediated Regulation of Gene Expression during Myogenic Differentiation, Maura H. Parker
Role of ErbB3 During Mammary Tumorigenesis, Niki Sharan
IMMUNE REGULATORY MECHANISMS OF THE RESPIRATORY MUCOSA, FILIP KRZYSZTOF SWIRSKI
The role of β-integrin signaling in mammary gland tumourigenesis, Donald E. White
Investigation of Immunomodulatory Concepts in a Murine Model of Airway Mucosal Sensitization to Innocuous Antigen, Ryan E. Wiley
Theses/Dissertations from 2003
Molecular Abnormalities in Postmortem Brains of Subjects with Mood Disorders, Dariush Dowlatshahi
GENERATION OF IMMUNE RESPONSES IN EXPERIMENTAL ALLERGIC AIRWAY INFLAMMATION, Beata Urszula Gajewska
Chromatin remodeling and myogenesis, Claire Palmer
Studies on the Molecular Mechanisms of Hydrogen Peroxide-mediated Regulation of Cell Proliferation, Thomas J. Preston
Cytokine regulation of immune responses in he respiratory mucosa, Stacey Ritz
Temporary Sensory Protection of Denervated and Skeletal Muscle: A Quantitative Ultrastructural and Functional Assessment of Nerve and Muscle, Karen Lynn Veltri
IMMUNIZATION VIA THE COLONIC MUCOSA USING ADENOVIRAL VECTORS, QING ZHU
Theses/Dissertations from 2002
The Neuroprotective Properties of Mood Stabilizers: from Gene Regulation to Ultrastructural Characterization, Christopher D. Brown
CELLULAR AND MOLECULAR HOST-PATHOGEN INTERACTIONS DURING CHLAMYDIA PNEUMONIAE INFECTION, Brian K. Coombes
ULTRAFILTRATION AND DYSFUNCTION IN PERITONEAL DIALYSIS: THE ROLE OF INFLAMMATION, FIBROSIS, AND ANGIOGENESIS, Peter J. Margetts
THE ROLE OF THE PEA3 SUBFAMILY ETS GENES IN MAMMARY TUMORIGENESIS: USE OF TRANSGENIC MOUSE MODELS OF BREAST CANCER, TREVOR G. SHEPHERD
NEUROPROTECTIVE PROPERTIES OF CILIARY NEUROTROPHIC FACTOR ON THE SURVIVAL OF AXOTOMIZED RETINAL GANGLION CELLS IN VIVO, BRIAN A. VAN ADEL
MECHANISM OF ENHANCED INTESTINAL TRANSEPITHELIAL ANTIGEN TRANSPORT IN FOOD ALLERGY: ROLE OF IgE, IL-4, AND CD23/FcεII, LINDA Chia-Hui YU
Theses/Dissertations from 2001
Cognitive processes in emotion recognition: A pet study of men, women and adults with autism, Geoffrey Brian Charles Hall
EFFECTS OF NEUROTROPHIC AND ANTI-INFLAMMATORY CYTOKINES ONF THE SURVIVAL OF AXOTOMIZED RETINAL GANGLION CELLS, Paulo D. Koeberle
A structure-function relationship study involving the first epidermal growth factor-like domain of human coagulation factor VII, Blair John Normand Leonard
Theses/Dissertations from 2000
Effect of 17-beta-estradiol and gender on substrate metabolism in humans during exercise, Sherry Lee Carter
Identification of the effects of proline-leucine-glycine-NH(2) (PLG) on D(2)-dopamine receptor function and gene expression in the rat brain, Williard James Costain
The effects of mutagenesis on the reactive centre loop of two thrombin-inhibitory serpins, antithrombin and heparin cofactor II, Michael Andrew Cunningham
Investigations of platelet IgG in immune and non-immune thrombocytopenia, Mary Hughes
The regulation of carbohydrate and lactate metabolism in exercising human skeletal muscle, Michelle Parolin MacDonald
Interactions of vampire bat plasminogen activator, tissue-type plasminogen activator, and TNK-variants with fibrin, fibrinogen, and the fibrin fragment (DD)E, Ronald J. Stewart
The contribution of mitochondrial function to the energetics of cell cycle progression, Susan Sweet
Modulation of ozone-induced airway hyperresponsiveness by cyclooxygenase and nitric oxide synthase, Edward G. (Ted) Watson
The role of monocyte/macrophages in immune-mediated epithelial pathophysiology: Implications for inflammatory bowel disease, Mehri Zareie
Theses/Dissertations from 1999
Isolation and characterization of caveolae from canine airway and intestinal smooth muscle, Peter James Darby
A Structural Basis for the Genesis of Hypertension in the Spontaneously Hypertensive Rat, Jeffrey G. Dickhout
Hydrogen peroxide production and autocrine proliferation control, Ann M. Dorward
Endothelin response and reactive oxygen in coronary artery smooth muscle, Adel B. Elmoselhi
Intrinsic electrophysiological properties of interstitial cells of Cajal and smooth muscle cells, Jonathan Cheuk Fung Lee
Angiogenesis and immune regulation in tumor gene therapy, Steve Frank Gyorffy
The influence of extracellular pH on human skeletal muscle metabolism, Melanie G. Hollidge-Horvat
Strain-dependent phenotype of p130- and p107-deficient mice, Jennifer E. LeCouter
In vivo assessment of the relation between trabecular bone structure in the radius and gender, aging, mechanical loading and fracture, Norma J. MacIntyre
Cellular origin and regulation of the electrical slow wave in the murine small intestinal musculature, John Malysz
Tumour gene therapy using adenoviral vectors expressing tumour necrosis factor alpha, Robert Anthony Marr
Rates of bone loss in postmenopausal women: Relationship to calcium intake, calcium absorption, serum estrogen, body mass and physical activity, Patricia Hoover Pearson
Cloning of the SH2-containing inositol 5-phosphatase (SHIP) and characterization of its role during erythroid differentiation, Josie Ursini
Theses/Dissertations from 1998
Transepithelial Transport of Antigen: Novel Mechanisms in Food Allergy, Maria Cecilia Berin
Cytokime therapy of cancer by gene transfer, Peter C. Emtage
Pharmacological modulation of allergen-induced airway inflammation, Gail M. Gauvreau
Mucosal Vaccination with a Novel Microarticle Delivery System, Phillippa Luise Heritage
Interaction of Thrombin with Prothrombin Fragment 2, Heparin Cofactor II, and Fibrin, Patricia C. Y. Liaw
G PROTEINS AND PARKINSON'S DISEASE: THE ROLE OF SIGNAL TRANSUCING G PROTEINS IN MEDIATING DOPAMINE RECEPTOR SUPERSENSITIVITY IN PARKINSON'S DISEASE, Eric R. Marcotte
Acute Stress-Induced Pathophysiology of Intestinal Epithelium in Stress Susceptible Wistar Kyoto Rats, Paul Russell Saunders