Date of Award


Degree Type


Degree Name

Master of Engineering (ME)


Chemical Engineering


Professor A.E. Hamielec


Herein is reported a theoretical and experimental evaluation of liquid exclusion chromatography (LEC) for the measurement of particle size distribution (PSD) and diameter averages for colloidal spheres of various compositions.

Correction factors for axial dispersion have been derived for a general detector whose signal is proportional to the number of particles time particle diameter to the power gamma (γ) where γ varies from zero to six. This general detector includes a turbidimeter (γ=6) and a refractometer (γ=3).

Equipment and operational variables and their effect on resolution were investigated experimentally. These included packing and pore sizes, bed length and carrier liquid flowrate.

The use of LEC for the off-line monitoring of the growth of latex particles was investigated for the surfactant-free emulsion polymerization of two monomer systems-styrene and vinyl acetate.

LEC can be used to quantitatively measure the size distribution and diameter averages of both organic latices and inorganic particles in the submicron range in an off-line analytical mode. LEC is sufficiently rapid for the off-line monitoring of latex particle growth in emulsion polymerization. With some modification it could be used in an online mode as a sensor for reactor control.