Date of Award
Doctor of Philosophy (PhD)
Professor C.J.L. Lock
The structure of some of the products obtained from the aquation of cis-PtCl₂ (NH₃)₂ were determined. They help clarify the complex nature of what was considered to be a simple chemical reaction.
The products of the reactions between K₂PtCl₄ and various alicyclic amines were also studied by X-ray crystallography and vibrational spectroscopy. The variety of products obtained was considerably greater than was expected and indicates the need for better control of the purity of compounds used in animal tests. The structures of some of these compounds also suggest a possible reason for their low toxicity.
Zvagulis, Maruta, "Structures and Spectra of Some Platinum Anti-Cancer Complexes" (1980). Open Access Dissertations and Theses. Paper 583.